PDB entry 1fap

View 1fap on RCSB PDB site
Description: the structure of the immunophilin-immunosuppressant fkbp12-rapamycin complex interacting with human frap
Class: complex (isomerase/kinase)
Keywords: fkbp12, frap, rapamycin, complex (isomerase/kinase)
Deposited on 1996-03-15, released 1997-07-23
The last revision prior to the SCOP 1.75 freeze date was dated 1997-07-23, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.193
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: fk506-binding protein
  Species: HOMO SAPIENS
  Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY
  Database cross-references and differences (RAF-indexed):
  • Uniprot P62942 (0-106)
  Domains in SCOP 1.75: d1fapa_
• Chain 'B':
  Compound: frap
  Species: HOMO SAPIENS
  Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY
  Database cross-references and differences (RAF-indexed):
  • Uniprot P42345 (0-94)
  Domains in SCOP 1.75: d1fapb_
• Heterogens: RAP, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1fapA (A:)
  gvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirgwe
  egvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1fapB (B:)
  rvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrd
  lmeaqewcrkymksgnvkdltqawdlyyhvfrris