PDB entry 1es7

View 1es7 on RCSB PDB site
Description: complex between bmp-2 and two bmp receptor ia ectodomains
Class: cytokine
Keywords: protein-protein complex, three finger toxin fold, receptor-ligand complex, cytokine receptor, TGF beta superfamily
Deposited on 2000-04-07, released 2000-10-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.191
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: bone morphogenetic protein-2
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1es7a_
  • Chain 'B':
    Compound: bone morphogenetic protein receptor ia
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1es7b_
  • Chain 'C':
    Compound: bone morphogenetic protein-2
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1es7c_
  • Chain 'D':
    Compound: bone morphogenetic protein receptor ia
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1es7d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1es7A (A:)
    maqakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnst
    nhaivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1es7A (A:)
    kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
    nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1es7B (B:)
    tlpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdsp
    kaqlrrtieccrtnlcnqylqptlppvvi
    

    Sequence, based on observed residues (ATOM records): (download)
    >1es7B (B:)
    tlpflkcycsghcpddainntcitnghcfaiieedettlasgcmkyegsdfqckdspkaq
    lrrtieccrtnlcnqylqptlpp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1es7C (C:)
    maqakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnst
    nhaivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1es7C (C:)
    kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
    nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1es7D (D:)
    tlpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdsp
    kaqlrrtieccrtnlcnqylqptlppvvi
    

    Sequence, based on observed residues (ATOM records): (download)
    >1es7D (D:)
    tlpflkcycsghcpddainntcitnghcfaiieedettlasgcmkyegsdfqckdspkaq
    lrrtieccrtnlcnqylqptlppvvi