PDB entry 1df0

View 1df0 on RCSB PDB site
Description: crystal structure of m-calpain
Class: hydrolase
Keywords: cysteine protease, calmodulin, papain, catalytic triad, zymogen activation, calcium, c2 domain, protease, zymogen, calpain
Deposited on 1999-11-16, released 2000-06-21
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.223
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: m-calpain
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07009 (Start-699)
      • engineered (104)
    Domains in SCOP 1.75: d1df0a1, d1df0a2, d1df0a3
  • Chain 'B':
    Compound: calpain
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1df0b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1df0A (A:)
magiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpsfpalpsslgf
kelgpyssktrgiewkrpteicadpqfiiggatrtdicqgalgdswllaaiasltlneei
larvvpldqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsal
lekayakingcyealsggattegfedftggiaewyelrkpppnlfkiiqkalekgsllgc
siditsaadseavtyqklvkghaysvtgaeevessgslqklirirnpwgqvewtgkwndn
cpswntvdpevranlterqedgefwmsfsdflrhysrleicnltpdtltcdsykkwkltk
mdgnwrrgstaggcrnypntfwmnpqylikleeededdedgergctflvgliqkhrrrqr
kmgedmhtigfgiyevpeeltgqtnihlsknfflttrarersdtfinlrevlnrfklppg
eyvlvpstfephkngdfcirvfsekkadyqtvddeieanieeieaneedigdgfrrlfaq
lagedaeisafelqtilrrvlakrediksdgfsietckimvdmldedgsgklglkefyil
wtkiqkyqkiyreidvdrsgtmnsyemrkaleeagfklpcqlhqvivarfaddeliidfd
nfvrclvrleilfkifkqldpentgtiqldliswlsfsvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1df0A (A:)
agiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpsfpalpsslgfk
elgpyssktrgiewkrpteicadpqfiiggatrtdicqgalgdswllaaiasltlneeil
arvvpldqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsall
ekayakingcyealsggattegfedftggiaewyelrkpppnlfkiiqkalekgsllgcs
idighaysvtgaeevqklirirnpwgqgefwmsfsdflrhysrleicnltpdtltcdsyk
kwkltkmdgnwrrgstaggcrnypntfwmnpqylikleeededdedgrgctflvgliqkh
rrrqrkmgedmhtigfgiyevsknffltersdtfinlrevlnrfklppgeyvlvpstfep
hkngdfcirvfsekkadyqtvddeieanieeianeedigdgfrrlfaqlagedaeisafe
lqtilrrvlakksdgfsietckimvdmldedgsgklglkefyilwtkiqkyqkiyreidv
drsgtmnsyemrkaleeagfklpcqlhqvivarfaddeliidfdnfvrclvrleilfkif
kqldpentgtiqldliswlsfsvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1df0B (B:)
mhysnieaneseeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtc
rsmvavmdsdttgklgfeefkylwnnikkwqgiykrfdtdrsgtigsnelpgafeaagfh
lnqhiysmiirrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlql
tmys

    Sequence, based on observed residues (ATOM records): (download) 
    >1df0B (B:)
neseeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmd
sdttgklgfeefkylwnnikkwqgiykrfdtdrsgtigsnelpgafeaagfhlnqhiysm
iirrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlqltmys