PDB entry 1bx2

View 1bx2 on RCSB PDB site
Description: crystal structure of hla-dr2 (dra*0101,drb1*1501) complexed with a peptide from human myelin basic protein
Class: immune system
Keywords: hla-dr2, myelin basic protein, multiple sclerosis, autoimmunity, immune system
Deposited on 1998-10-12, released 1998-10-21
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.238
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (hla-dr2)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1bx2a1, d1bx2a2
  • Chain 'B':
    Compound: protein (hla-dr2)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1bx2b1, d1bx2b2
  • Chain 'C':
    Compound: protein (hla-dr2)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1BX2 (0-End)
  • Chain 'D':
    Compound: protein (hla-dr2)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1bx2d1, d1bx2d2
  • Chain 'E':
    Compound: protein (hla-dr2)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1bx2e1, d1bx2e2
  • Chain 'F':
    Compound: protein (hla-dr2)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1BX2 (Start-14)
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1bx2A (A:)
    keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
    niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
    lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1bx2B (B:)
    trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
    sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvsgf
    ypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsvts
    pltvewrarse
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1bx2D (D:)
    keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
    niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
    lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1bx2E (E:)
    trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
    sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvsgf
    ypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsvts
    pltvewrarse
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bx2E (E:)
    trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
    sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvsgf
    ypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsvts
    pltvewrar
    

  • Chain 'F':
    No sequence available.