PDB entry 1bth

View 1bth on RCSB PDB site
Description: structure of thrombin complexed with bovine pancreatic trypsin inhibitor
Class: complex (serine protease/inhibitor)
Keywords: thrombin inhibitor, serine proteinase kunitz-like inhibitor, (serine protease/inhibitor), complex (serine protease/inhibitor) complex
Deposited on 1996-12-03, released 1997-12-24
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.196
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00734 (0-End)
      • conflict (148)
      • engineered (201)
    Domains in SCOPe 2.03: d1bth.1
  • Chain 'J':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1bth.2
  • Chain 'K':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00734 (0-End)
      • conflict (148)
      • engineered (201)
    Domains in SCOPe 2.03: d1bth.2
  • Chain 'L':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1bth.1
  • Chain 'P':
    Compound: bovine pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1bthp_
  • Chain 'Q':
    Compound: bovine pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1bthq_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1bthH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1bthH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvi

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1bthJ (J:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >1bthJ (J:)
geadcglrplfekksledkterellesyidg

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1bthK (K:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1bthK (K:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvi

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1bthL (L:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >1bthL (L:)
geadcglrplfekksledkterellesyidg

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1bthP (P:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

  • Chain 'Q':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1bthQ (Q:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga