PDB entry 1ajx

View 1ajx on RCSB PDB site
Description: hiv-1 protease in complex with the cyclic urea inhibitor aha001
Class: aspartyl protease
Keywords: protease, aspartyl protease, non-peptide inhibitor, drug design, hiv-1
Deposited on 1997-05-11, released 1997-09-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.161
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: PROTEASE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ajxa_
  • Chain 'B':
    Compound: hiv-1 protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: PROTEASE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ajxb_
  • Heterogens: AH1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1ajxA (A:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1ajxB (B:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf