PDB entry 1a1r

View 1a1r on RCSB PDB site
Description: hcv ns3 protease domain:ns4a peptide complex
Class: Viral protein
Keywords: viral protein, serine protease, nonstructural proteins, cofactor peptide, helicase
Deposited on 1997-12-15, released 1998-06-17
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.216
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ns3 protein
    Species: Hepatitis C virus
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27958 (Start-189)
      • variant (83)
    Domains in SCOP 1.75: d1a1r.1
  • Chain 'B':
    Compound: ns3 protein
    Species: Hepatitis C virus
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27958 (Start-189)
      • variant (83)
    Domains in SCOP 1.75: d1a1r.2
  • Chain 'C':
    Compound: ns4a protein
    Species: Hepatitis C virus
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27958 (2-End)
      • variant (3)
    Domains in SCOP 1.75: d1a1r.1
  • Chain 'D':
    Compound: ns4a protein
    Species: Hepatitis C virus
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27958 (2-20)
      • variant (3)
    Domains in SCOP 1.75: d1a1r.2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1a1rA (A:)
asmtggqqmgapitayaqqtrgllgciitsltgrdknqvegevqivstatqtflatcing
vcwtvyhgagtrtiaspkgpviqmytnvdqdlvgwpapqgsrsltpctcgssdlylvtrh
advipvrrrgdsrgsllsprpisylkgssggpllcptghavglfraavctrgvakavdfi
pvenlettmrgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1a1rA (A:)
vegevqivstatqtflatcingvcwtvyhgagtrtiaspkgpviqmytnvdqdlvgwpap
qgsrsltpctcgssdlylvtrhadvipvrrrgdsrgsllsprpisylkgssggpllcptg
havglfraavctrgvakavdfipvenlettmr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1a1rB (B:)
asmtggqqmgapitayaqqtrgllgciitsltgrdknqvegevqivstatqtflatcing
vcwtvyhgagtrtiaspkgpviqmytnvdqdlvgwpapqgsrsltpctcgssdlylvtrh
advipvrrrgdsrgsllsprpisylkgssggpllcptghavglfraavctrgvakavdfi
pvenlettmrgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1a1rB (B:)
pitayaqqtrgllgciitsltgrdknqvegevqivstatqtflatcingvcwtvyhgagt
rtiaspkgpviqmytnvdqdlvgwpapqgsrsltpctcgssdlylvtrhadvipvrrrgd
srgsllsprpisylkgssggpllcptghavglfraavctrgvakavdfipvenlettmr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1a1rC (C:)
kkgsvvivgrivlsgkpaiipkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1a1rC (C:)
gsvvivgrivlsgkpa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1a1rD (D:)
kkgsvvivgrivlsgkpaiipkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1a1rD (D:)
kgsvvivgrivlsgkpaiipk