Lineage for d1umdc_ (1umd C:)

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 581036Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 581037Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 581340Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (4 proteins)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 581344Protein Branched-chain alpha-keto acid dehydrogenase, PP module [88767] (2 species)
  7. 581360Species Thermus thermophilus [TaxId:274] [102337] (4 PDB entries)
  8. 581362Domain d1umdc_: 1umd C: [99602]
    Other proteins in same PDB: d1umdb1, d1umdb2, d1umdd1, d1umdd2
    complexed with coi, mg, tdp

Details for d1umdc_

PDB Entry: 1umd (more details), 1.9 Å

PDB Description: branched-chain 2-oxo acid dehydrogenase (e1) from thermus thermophilus hb8 with 4-methyl-2-oxopentanoate as an intermediate

SCOP Domain Sequences for d1umdc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1umdc_ c.36.1.11 (C:) Branched-chain alpha-keto acid dehydrogenase, PP module {Thermus thermophilus}
hrfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilirtgkts
fiapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatkadpnkg
rqmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatsegdwya
ginfaavqgapavfiaennfyaisvdyrhqthsptiadkahafgipgylvdgmdvlasyy
vvkeaverarrgegpslvelrvyrygphssadddsryrpkeevafwrkkdpiprfrrfle
arglwneeweedvreeiraelerglkeaeeagpvppewmfedvfaekpwhllrqeallke
e

SCOP Domain Coordinates for d1umdc_:

Click to download the PDB-style file with coordinates for d1umdc_.
(The format of our PDB-style files is described here.)

Timeline for d1umdc_: