Lineage for d1um9c_ (1um9 C:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108723Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5 protein domains)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 2108727Protein Branched-chain alpha-keto acid dehydrogenase, PP module [88767] (2 species)
  7. 2108748Species Thermus thermophilus [TaxId:274] [102337] (4 PDB entries)
  8. 2108754Domain d1um9c_: 1um9 C: [99584]
    Other proteins in same PDB: d1um9b1, d1um9b2, d1um9d1, d1um9d2
    complexed with so4

Details for d1um9c_

PDB Entry: 1um9 (more details), 2.2 Å

PDB Description: branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in apo-form
PDB Compounds: (C:) 2-oxo acid dehydrogenase alpha subunit

SCOPe Domain Sequences for d1um9c_:

Sequence, based on SEQRES records: (download)

>d1um9c_ c.36.1.11 (C:) Branched-chain alpha-keto acid dehydrogenase, PP module {Thermus thermophilus [TaxId: 274]}
rfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilirtgktsf
iapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatkadpnkgr
qmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatsegdwyag
infaavqgapavfiaennfyaisvdyrhqthsptiadkahafgipgylvdgmdvlasyyv
vkeaverarrgegpslvelrvyrygphssadddsryrpkeevafwrkkdpiprfrrflea
rglwneeweedvreeiraelerglkeaeeagpvppewmfedvfaekpwhllrqeallkee
l

Sequence, based on observed residues (ATOM records): (download)

>d1um9c_ c.36.1.11 (C:) Branched-chain alpha-keto acid dehydrogenase, PP module {Thermus thermophilus [TaxId: 274]}
rfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilirtgktsf
iapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatkadpnkgr
qmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatsegdwyag
infaavqgapavfiaennfptiadkahafgipgylvdgmdvlasyyvvkeaverarrgeg
pslvelrvyrygphssaddrkkdpiprfrrflearglwneeweedvreeiraelerglke
aeeagpvppewmfedvfaekpwhllrqeallkeel

SCOPe Domain Coordinates for d1um9c_:

Click to download the PDB-style file with coordinates for d1um9c_.
(The format of our PDB-style files is described here.)

Timeline for d1um9c_: