SCOP 1.73: Domain d1uk4a_: 1uk4 A:

Lineage for d1uk4a_ (1uk4 A:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (3 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (3 species)
   contains an extra alpha-helical domain

7. Species SARS coronavirus [TaxId:227859] [89349] (6 PDB entries)

8. Domain d1uk4a_: 1uk4 A: [99485]

Details for d1uk4a_

PDB Entry: 1uk4, 2.5 Å

PDB Description: Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor

PDB Compounds: (A:) 3C-like proteinase

SCOP Domain Sequences for d1uk4a_:

Sequence; same for both SEQRES and ATOM records:

>d1uk4a_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {SARS coronavirus [TaxId: 227859]}
frkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllirks
nhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyngsp
sgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegkfy
gpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynyepl
tqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqcsg
v

Timeline for d1uk4a_:

• d1uk4a_ first appeared in SCOP 1.67
  
• d1uk4a_ appears in SCOP 1.71
  
• d1uk4a_ appears in SCOP 1.75
  
• d1uk4a_ appears in the current release, SCOPe 2.08