SCOP 1.75: Domain d1ub5h2: 1ub5 H:117-214

Lineage for d1ub5h2 (1ub5 H:117-214)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (7 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88576] (373 PDB entries)
   Uniprot P01864 # GCAB_MOUSE Ig gamma-2A chain C region secreted form (B allele)
   Uniprot P01863 #GCAA_MOUSE Ig gamma-2A chain C region, A allele; 86% sequence identity
   SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form)
   Uniprot P01868 # GC1_MOUSE Ig gamma-1 chain C region secreted form
   Uniprot P01864 # GCAB_MOUSE (P01864) Ig gamma-2A chain C region
   Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region
   Uniprot P01863 # GCAA_MOUSE Ig gamma-2A chain C region, A allele
   SQ NA # part of Fab 28 against HIV-1 RT
   Uniprot P01868 #
   GC1_MOUSE Ig gamma-1 chain C region secreted form
   Uniprot P01864 # GCAB_MOUSE Ig gamma-2A chain C region secreted form (B allele) ! Uniprot P01863 #GCAA_MOUSE Ig gamma-2A chain C region, A allele; 86% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form) ! Uniprot P01868 # GC1_MOUSE Ig gamma-1 chain C region secreted form ! Uniprot P01864 # GCAB_MOUSE (P01864) Ig gamma-2A chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! Uniprot P01863 # GCAA_MOUSE Ig gamma-2A chain C region, A allele ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01868 # ! GC1_MOUSE Ig gamma-1 chain C region secreted form

8. Domain d1ub5h2: 1ub5 H:117-214 [99148]
   Other proteins in same PDB: d1ub5a1, d1ub5b1, d1ub5b2, d1ub5h1, d1ub5l1, d1ub5l2
   part of blue fluorescent Fab 19G2

Details for d1ub5h2

PDB Entry: 1ub5, 2 Å

PDB Description: Crystal structure of Antibody 19G2 with hapten at 100K

PDB Compounds: (H:) antibody 19G2, alpha chain

SCOP Domain Sequences for d1ub5h2:

Sequence; same for both SEQRES and ATOM records:

>d1ub5h2 b.1.1.2 (H:117-214) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Mouse (Mus musculus) [TaxId: 10090]}
akttppsvypaapgcgdttgssvtlgclvkgyfpepvtvtwnsggssvhtfpallqsgly
tmsssvtvpsstwpstvtcsvahpassttvdkkle

Timeline for d1ub5h2:

• d1ub5h2 first appeared in SCOP 1.67
  
• d1ub5h2 appears in SCOP 1.73
  
• d1ub5h2 appears in SCOPe 2.01
  
• d1ub5h2 appears in the current release, SCOPe 2.08