SCOP 1.71: Domain d1ub5b1: 1ub5 B:1-113

Lineage for d1ub5b1 (1ub5 B:1-113)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (126 PDB entries)

8. Domain d1ub5b1: 1ub5 B:1-113 [99145]
   Other proteins in same PDB: d1ub5a1, d1ub5a2, d1ub5b2, d1ub5h1, d1ub5h2, d1ub5l2
   part of blue fluorescent Fab 19G2
   complexed with spb

Details for d1ub5b1

PDB Entry: 1ub5, 2 Å

PDB Description: Crystal structure of Antibody 19G2 with hapten at 100K

SCOP Domain Sequences for d1ub5b1:

Sequence; same for both SEQRES and ATOM records:

>d1ub5b1 b.1.1.1 (B:1-113) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1}
divmtqaafsnpvtlgtsasiscrstksllhsngitylywylqkpgqspqlliyqmsnla
sgvpnrfsssgsgtdftlrisrveaedvgvyycaqnlelpptfgggtkleikr

Timeline for d1ub5b1:

• d1ub5b1 first appeared in SCOP 1.67
  
• d1ub5b1 appears in SCOP 1.69
  
• d1ub5b1 appears in SCOP 1.73
  
• d1ub5b1 appears in the current release, SCOPe 2.08