Lineage for d1t2fc1 (1t2f C:1-160)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2093044Family c.2.1.5: LDH N-terminal domain-like [51848] (9 protein domains)
  6. 2093083Protein Lactate dehydrogenase [51859] (18 species)
  7. 2093137Species Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [63939] (2 PDB entries)
  8. 2093142Domain d1t2fc1: 1t2f C:1-160 [99092]
    Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
    complexed with nad, oxq

Details for d1t2fc1

PDB Entry: 1t2f (more details), 3 Å

PDB Description: Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid
PDB Compounds: (C:) L-lactate dehydrogenase B chain

SCOPe Domain Sequences for d1t2fc1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1t2fc1 c.2.1.5 (C:1-160) Lactate dehydrogenase {Human (Homo sapiens), heart isoform (H chain) [TaxId: 9606]}

SCOPe Domain Coordinates for d1t2fc1:

Click to download the PDB-style file with coordinates for d1t2fc1.
(The format of our PDB-style files is described here.)

Timeline for d1t2fc1: