SCOPe 2.07: Domain d1sx8a_: 1sx8 A:

Lineage for d1sx8a_ (1sx8 A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (37 families)

5. Family c.52.1.2: Restriction endonuclease EcoRV [52984] (1 protein)
   automatically mapped to Pfam PF09233

6. Protein Restriction endonuclease EcoRV [52985] (1 species)

7. Species Escherichia coli [TaxId:562] [52986] (30 PDB entries)

8. Domain d1sx8a_: 1sx8 A: [99025]
   protein/DNA complex; complexed with mn

Details for d1sx8a_

PDB Entry: 1sx8, 2.15 Å

PDB Description: ecorv bound to cognate dna and mn2+

PDB Compounds: (A:) Type II restriction enzyme EcoRV

SCOPe Domain Sequences for d1sx8a_:

Sequence, based on SEQRES records:

>d1sx8a_ c.52.1.2 (A:) Restriction endonuclease EcoRV {Escherichia coli [TaxId: 562]}
slrsdlinalydenqkydvcgiisaegkiyplgsdtkvlstifelfsrpiinkiaekhgy
iveepkqqnhypdftlykpsepnkkiaidiattytnkenekikftlggytsfirnntkni
vypfdqyiahwiigyvytrvatrksslktyninelneipkpykgvkvflqdkwviagdla
gsgnttnigsihahykdfvegkgifdsedefldywrnyertsqlrndkynniseyrnwiy
rgrk

Sequence, based on observed residues (ATOM records):

>d1sx8a_ c.52.1.2 (A:) Restriction endonuclease EcoRV {Escherichia coli [TaxId: 562]}
slrsdlinalydenqkydvcgiisaegkiyplgsdtkvlstifelfsrpiinkiaekhgy
iveepkqqnhypdftlykpsepnkkiaidiattytnkenekikftlggytsfirnntkni
vypfdqyiahwiigyvytrvksslktyninelneipkpykgvkvflqdkwviagdlagsg
nttnigsihahykdfvegkgifdsedefldywrnyertsqlrndkynniseyrnwiyrgr
k

Timeline for d1sx8a_:

• d1sx8a_ first appeared in SCOP 1.67
  
• d1sx8a_ appears in SCOPe 2.06
  
• d1sx8a_ appears in the current release, SCOPe 2.08