SCOPe 2.05: Domain d1sj0a_: 1sj0 A:

Lineage for d1sj0a_ (1sj0 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (61 PDB entries)
   Uniprot P03372 307-551

8. Domain d1sj0a_: 1sj0 A: [98893]
   complexed with e4d

Details for d1sj0a_

PDB Entry: 1sj0, 1.9 Å

PDB Description: human estrogen receptor alpha ligand-binding domain in complex with the antagonist ligand 4-d

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d1sj0a_:

Sequence, based on SEQRES records:

>d1sj0a_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemlda
hrlha

Sequence, based on observed residues (ATOM records):

>d1sj0a_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcvvplydlllemldahr
lha

Timeline for d1sj0a_:

• d1sj0a_ first appeared in SCOP 1.67
  
• d1sj0a_ appears in SCOPe 2.04
  
• d1sj0a_ appears in SCOPe 2.06
  
• d1sj0a_ appears in the current release, SCOPe 2.08