SCOP 1.73: Domain d1sh2a_: 1sh2 A:

Lineage for d1sh2a_ (1sh2 A:)

1. Root: SCOP 1.73

2. Class e: Multi-domain proteins (alpha and beta) [56572] (53 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (2 proteins)

6. Protein Viral RNA polymerase [56695] (9 species)

7. Species Norwalk virus [TaxId:11983] [103400] (3 PDB entries)

8. Domain d1sh2a_: 1sh2 A: [98878]

Details for d1sh2a_

PDB Entry: 1sh2, 2.3 Å

PDB Description: Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic)

PDB Compounds: (A:) RNA polymerase

SCOP Domain Sequences for d1sh2a_:

Sequence; same for both SEQRES and ATOM records:

>d1sh2a_ e.8.1.4 (A:) Viral RNA polymerase {Norwalk virus [TaxId: 11983]}
gtycgapilgpgsapklstktkfwrsstaplppgtyepaylggkdprvkggpslqqvmrd
qlkpfteprgkppkpsvleaakktiinvleqtidppdkwsfaqacasldkttssghphhm
rkndcwngesftgkladqaskanlmfeegknmtpvytgalkdelvktdkiygkikkrllw
gsdlatmircarafgglmdelkthcvtlpirvgmnmnedgpiiferhsryryhydadysr
wdstqqravlaaaleimvkfssephlaqvvaedllspsvvdvgdftisineglpsgvpct
sqwnsiahwlltlcalsevtnlspdiiqanslfsfygddeivstdikldpekltaklkey
glkptrpdktegplvisedlngltflrrtvtrdpagwfgkleqssilrqmywtrgpnhed
psetmiphsqrpiqlmsllgeaalhgpafyskisklviaelkeggmdfyvprqepmfrwm
rfsdlstwegdrnlapsfvned

Timeline for d1sh2a_:

• d1sh2a_ first appeared in SCOP 1.67
  
• d1sh2a_ appears in SCOP 1.71
  
• d1sh2a_ appears in SCOP 1.75
  
• d1sh2a_ appears in the current release, SCOPe 2.08