SCOPe 2.02: Domain d1sa1a1: 1sa1 A:2-245

Lineage for d1sa1a1 (1sa1 A:2-245)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.32: Tubulin nucleotide-binding domain-like [52489] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.32.1: Tubulin nucleotide-binding domain-like [52490] (1 family)

5. Family c.32.1.1: Tubulin, GTPase domain [52491] (3 proteins)

6. Protein Tubulin alpha-subunit [52494] (3 species)

7. Species Cow (Bos taurus) [TaxId:9913] [63989] (4 PDB entries)

8. Domain d1sa1a1: 1sa1 A:2-245 [98778]
   Other proteins in same PDB: d1sa1a2, d1sa1b1, d1sa1b2, d1sa1c2, d1sa1d1, d1sa1d2, d1sa1e_
   complexed with gdp, gtp, mg, pod

Details for d1sa1a1

PDB Entry: 1sa1, 4.2 Å

PDB Description: Tubulin-podophyllotoxin: stathmin-like domain complex

PDB Compounds: (A:) Tubulin alpha chain

SCOPe Domain Sequences for d1sa1a1:

Sequence, based on SEQRES records:

>d1sa1a1 c.32.1.1 (A:2-245) Tubulin alpha-subunit {Cow (Bos taurus) [TaxId: 9913]}
recisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagkh
vpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldr
irkladqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstav
vepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitas
lrfd

Sequence, based on observed residues (ATOM records):

>d1sa1a1 c.32.1.1 (A:2-245) Tubulin alpha-subunit {Cow (Bos taurus) [TaxId: 9913]}
recisihvgqagvqignacwelyclehgiqpdgqmpsdgddsfntffsetgagkhvprav
fvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkla
dqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepyn
siltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfd

Timeline for d1sa1a1:

• d1sa1a1 first appeared in SCOP 1.67
  
• d1sa1a1 appears in SCOPe 2.01
  
• d1sa1a1 appears in SCOPe 2.03
  
• d1sa1a1 appears in the current release, SCOPe 2.08