SCOP 1.71: Domain d1s8oa2: 1s8o A:226-548

Lineage for d1s8oa2 (1s8o A:226-548)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (35 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.11: Epoxide hydrolase [53525] (2 proteins)

6. Protein Mammalian epoxide hydrolase, C-terminal domain [53526] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102626] (2 PDB entries)

8. Domain d1s8oa2: 1s8o A:226-548 [98737]
   Other proteins in same PDB: d1s8oa1
   complexed with p6g

Details for d1s8oa2

PDB Entry: 1s8o, 2.6 Å

PDB Description: Human soluble Epoxide Hydrolase

SCOP Domain Sequences for d1s8oa2:

Sequence; same for both SEQRES and ATOM records:

>d1s8oa2 c.69.1.11 (A:226-548) Mammalian epoxide hydrolase, C-terminal domain {Human (Homo sapiens)}
aplptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqag
yrvlamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwyma
lfypervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtf
kslfrasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnw
yrnmernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghw
tqmdkptevnqilikwldsdarn

Timeline for d1s8oa2:

• d1s8oa2 first appeared in SCOP 1.67
  
• d1s8oa2 appears in SCOP 1.69
  
• d1s8oa2 appears in SCOP 1.73
  
• d1s8oa2 appears in the current release, SCOPe 2.08