Lineage for d1s7gb_ (1s7g B:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2470834Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2470835Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2471146Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2471147Protein AF0112, Sir2 homolog (Sir2-AF2) [82380] (1 species)
  7. 2471148Species Archaeoglobus fulgidus [TaxId:2234] [82381] (3 PDB entries)
  8. 2471151Domain d1s7gb_: 1s7g B: [98643]
    complexed with 1pe, 2pe, apr, edo, nad, p6g, pg4, so4, zn

Details for d1s7gb_

PDB Entry: 1s7g (more details), 2.3 Å

PDB Description: Structural Basis for the Mechanism and Regulation of Sir2 Enzymes
PDB Compounds: (B:) NAD-dependent deacetylase 2

SCOPe Domain Sequences for d1s7gb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1s7gb_ c.31.1.5 (B:) AF0112, Sir2 homolog (Sir2-AF2) {Archaeoglobus fulgidus [TaxId: 2234]}
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrse

SCOPe Domain Coordinates for d1s7gb_:

Click to download the PDB-style file with coordinates for d1s7gb_.
(The format of our PDB-style files is described here.)

Timeline for d1s7gb_: