SCOPe 2.02: Domain d1s2qa1: 1s2q A:3-289,A:402-501

Lineage for d1s2qa1 (1s2q A:3-289,A:402-501)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (8 families)

5. Family c.3.1.2: FAD-linked reductases, N-terminal domain [51913] (18 proteins)
   C-terminal domain is alpha+beta is common for the family

6. Protein Monoamine oxidase B [69423] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69424] (28 PDB entries)

8. Domain d1s2qa1: 1s2q A:3-289,A:402-501 [98395]
   Other proteins in same PDB: d1s2qa2, d1s2qb2
   complexed with fad, ras

Details for d1s2qa1

PDB Entry: 1s2q, 2.07 Å

PDB Description: Crystal structure of MAOB in complex with N-propargyl-1(R)-aminoindan (Rasagiline)

PDB Compounds: (A:) amine oxidase [flavin-containing] b

SCOPe Domain Sequences for d1s2qa1:

Sequence; same for both SEQRES and ATOM records:

>d1s2qa1 c.3.1.2 (A:3-289,A:402-501) Monoamine oxidase B {Human (Homo sapiens) [TaxId: 9606]}
nkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsyvg
ptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwrtm
ddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethevsa
lwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidqtr
envlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvXfppgiltqygrv
lrqpvdriyfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvp
aqpitttflerhlpsvpgllrligltti

Timeline for d1s2qa1:

• d1s2qa1 first appeared in SCOP 1.67
  
• d1s2qa1 appears in SCOPe 2.01
  
• d1s2qa1 appears in SCOPe 2.03
  
• d1s2qa1 appears in the current release, SCOPe 2.08