| Class d: Alpha and beta proteins (a+b) [53931] (260 folds) |
| Fold d.135: The spindle assembly checkpoint protein mad2 [56018] (1 superfamily) core: alpha(2)-beta(2)-alpha-beta; mixed sheet: order 213 |
Superfamily d.135.1: The spindle assembly checkpoint protein mad2 [56019] (1 family) ![]() N- and C-termini undergo large conformational rearrangement upon ligand binding |
| Family d.135.1.1: The spindle assembly checkpoint protein mad2 [56020] (1 protein) |
| Protein The spindle assembly checkpoint protein mad2 [56021] (1 species) |
| Species Human (Homo sapiens) [TaxId:9606] [56022] (4 PDB entries) |
| Domain d1s2ha_: 1s2h A: [98385] mutant |
PDB Entry: 1s2h (more details)
SCOP Domain Sequences for d1s2ha_:
Sequence; same for both SEQRES and ATOM records: (download)
>d1s2ha_ d.135.1.1 (A:) The spindle assembly checkpoint protein mad2 {Human (Homo sapiens)}
malqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltllvttdle
likylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakddsapreks
qkaiqdeirsviaqitatvtflpllevscsfdlliytdkdlvvpekweesgpqfitnsee
vrlrsftttihkvnsmvaykipvnd
Timeline for d1s2ha_: