Lineage for d1rzga2 (1rzg A:114-214)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1290587Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 1292198Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (6 species)
  7. 1292202Species Human (Homo sapiens) [TaxId:9606] [88575] (177 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3) ! SQ NA # humanized antibody ! Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region ! SQ NA # engineered antibody
  8. 1292231Domain d1rzga2: 1rzg A:114-214 [98155]
    Other proteins in same PDB: d1rzga1, d1rzgb1, d1rzgb2, d1rzgc1, d1rzgd1, d1rzgd2
    part of anti HIV-1 gp120-reactive Fab 412D
    complexed with cys, suc

Details for d1rzga2

PDB Entry: 1rzg (more details), 2 Å

PDB Description: Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d
PDB Compounds: (A:) Fab 412d light chain

SCOPe Domain Sequences for d1rzga2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rzga2 b.1.1.2 (A:114-214) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1rzga2:

Click to download the PDB-style file with coordinates for d1rzga2.
(The format of our PDB-style files is described here.)

Timeline for d1rzga2: