Lineage for d1rzfl1 (1rzf L:2-108)

  1. Root: SCOP 1.67
  2. 362614Class b: All beta proteins [48724] (141 folds)
  3. 362615Fold b.1: Immunoglobulin-like beta-sandwich [48725] (22 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 362616Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 362617Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (24 proteins)
  6. 364057Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 364066Species Human (Homo sapiens), cluster 2 [TaxId:9606] [88536] (9 PDB entries)
  8. 364068Domain d1rzfl1: 1rzf L:2-108 [98152]
    Other proteins in same PDB: d1rzfh1, d1rzfh2, d1rzfl2
    part of anti HIV-1 gp120-reactive Fab E51
    complexed with gol, ioh

Details for d1rzfl1

PDB Entry: 1rzf (more details), 1.7 Å

PDB Description: Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51

SCOP Domain Sequences for d1rzfl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rzfl1 b.1.1.1 (L:2-108) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 2}

SCOP Domain Coordinates for d1rzfl1:

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Timeline for d1rzfl1:

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