Lineage for d1rz8d1 (1rz8 D:1-113)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 546419Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 546420Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)
  6. 546556Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 546633Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88544] (15 PDB entries)
  8. 546645Domain d1rz8d1: 1rz8 D:1-113 [98143]
    Other proteins in same PDB: d1rz8a1, d1rz8a2, d1rz8b2, d1rz8c1, d1rz8c2, d1rz8d2
    part of anti HIV-1 gp120-reactive Fab 17B

Details for d1rz8d1

PDB Entry: 1rz8 (more details), 2.3 Å

PDB Description: crystal structure of human anti-hiv-1 gp120-reactive antibody 17b

SCOP Domain Sequences for d1rz8d1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rz8d1 b.1.1.1 (D:1-113) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 1}
evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
gtlvtvss

SCOP Domain Coordinates for d1rz8d1:

Click to download the PDB-style file with coordinates for d1rz8d1.
(The format of our PDB-style files is described here.)

Timeline for d1rz8d1: