SCOPe 2.05: Domain d1ryfb_: 1ryf B:

Lineage for d1ryfb_ (1ryf B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rac [52595] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52596] (17 PDB entries)

8. Domain d1ryfb_: 1ryf B: [98100]
   alternative splicing variant of rac1
   complexed with gdp, mg

Details for d1ryfb_

PDB Entry: 1ryf, 1.75 Å

PDB Description: Alternative Splicing of Rac1 Generates Rac1b, a Self-activating GTPase

PDB Compounds: (B:) ras-related C3 botulinum toxin substrate 1 isoform Rac1b

SCOPe Domain Sequences for d1ryfb_:

Sequence, based on SEQRES records:

>d1ryfb_ c.37.1.8 (B:) Rac {Human (Homo sapiens) [TaxId: 9606]}
gsmqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdt
agqedydrlrplsypqtvgetygkditsrgkdkpiadvflicfslvspasfenvrakwyp
evrhhcpntpiilvgtkldlrddkdtieklkekkltpitypqglamakeigavkylecsa
ltqrglktvfdeairavlcpp

Sequence, based on observed residues (ATOM records):

>d1ryfb_ c.37.1.8 (B:) Rac {Human (Homo sapiens) [TaxId: 9606]}
gsmqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdt
iadvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlrddkdtieklkekk
ltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp

Timeline for d1ryfb_:

• d1ryfb_ first appeared in SCOP 1.67
  
• d1ryfb_ appears in SCOPe 2.04
  
• d1ryfb_ appears in SCOPe 2.06
  
• d1ryfb_ appears in the current release, SCOPe 2.08