SCOP 1.75: Domain d1rwbf_: 1rwb F:

Lineage for d1rwbf_ (1rwb F:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Glucose dehydrogenase [51784] (1 species)

7. Species Bacillus megaterium [TaxId:1404] [51785] (4 PDB entries)

8. Domain d1rwbf_: 1rwb F: [97973]
   complexed with nad; mutant

Details for d1rwbf_

PDB Entry: 1rwb, 2 Å

PDB Description: cooperative effect of two surface amino acid mutations (q252l and e170k) of glucose dehydrogenase from bacillus megaterium iwg3 for the stabilization of oligomeric state

PDB Compounds: (F:) glucose 1-dehydrogenase

SCOP Domain Sequences for d1rwbf_:

Sequence; same for both SEQRES and ATOM records:

>d1rwbf_ c.2.1.2 (F:) Glucose dehydrogenase {Bacillus megaterium [TaxId: 1404]}
mykdlegkvvvitgsstglgksmairfatekakvvvnyrskedeansvleeikkvggeai
avkgdvtvesdvinlvqsaikefgkldvminnaglenpvsshemslsdwnkvidtnltga
flgsreaikyfvendikgtvinmssvhekipwplfvhyaaskggmklmtktlaleyapkg
irvnnigpgaintpinaekfadpeqradvesmipmgyigepeeiaavaawlasseasyvt
gitlfadggmtlypsfqagrg

Timeline for d1rwbf_:

• d1rwbf_ first appeared in SCOP 1.67
  
• d1rwbf_ appears in SCOP 1.73
  
• d1rwbf_ appears in SCOPe 2.01
  
• d1rwbf_ appears in the current release, SCOPe 2.08