SCOP 1.69: Domain d1rukl1: 1ruk L:1-107

Lineage for d1rukl1 (1ruk L:1-107)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (126 PDB entries)

8. Domain d1rukl1: 1ruk L:1-107 [97861]
   Other proteins in same PDB: d1rukh1, d1rukh2, d1rukl2
   part of cationic cyclization catalytic Fab 4C6

Details for d1rukl1

PDB Entry: 1ruk, 1.4 Å

PDB Description: Crystal structure (C) of native cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 9-1

SCOP Domain Sequences for d1rukl1:

Sequence; same for both SEQRES and ATOM records:

>d1rukl1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1}
dvvmtqspktisvtigqpasisckssqrllnsngktflnwllqrpgqspkrliylgtkld
sgvpdrftgsgsgtdftlkisrveaedlgvyycwqgthfpytfgggtkleik

Timeline for d1rukl1:

• d1rukl1 first appeared in SCOP 1.67
  
• d1rukl1 appears in SCOP 1.71
  
• d1rukl1 appears in the current release, SCOPe 2.08