Lineage for d1rp7a1 (1rp7 A:471-700)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108389Family c.36.1.6: TK-like Pyr module [88735] (2 protein domains)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 2108390Protein Pyruvate dehydrogenase E1 component, Pyr module [88739] (1 species)
    E1A and E1B fused together in a single-chain protein
  7. 2108391Species Escherichia coli [TaxId:562] [88740] (6 PDB entries)
  8. 2108400Domain d1rp7a1: 1rp7 A:471-700 [97702]
    Other proteins in same PDB: d1rp7a2, d1rp7a3, d1rp7b2, d1rp7b3
    complexed with mg, tzd

Details for d1rp7a1

PDB Entry: 1rp7 (more details), 2.09 Å

PDB Description: e. coli pyruvate dehydrogenase inhibitor complex
PDB Compounds: (A:) Pyruvate dehydrogenase E1 component

SCOPe Domain Sequences for d1rp7a1:

Sequence, based on SEQRES records: (download)

>d1rp7a1 c.36.1.6 (A:471-700) Pyruvate dehydrogenase E1 component, Pyr module {Escherichia coli [TaxId: 562]}
eklelpslqdfgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeg
lfrqigiyspngqqytpqdreqvayykedekgqilqeginelgagcswlaaatsystnnl
pmipfyiyysmfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsl
tipncisydpayayevavimhdglermygekqenvyyyittlnenyhmpa

Sequence, based on observed residues (ATOM records): (download)

>d1rp7a1 c.36.1.6 (A:471-700) Pyruvate dehydrogenase E1 component, Pyr module {Escherichia coli [TaxId: 562]}
eklelpslqdfgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeg
lfrqigiyspedekgqilqeginelgagcswlaaatsystnnlpmipfyiyysmfgfqri
gdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipncisydpayayeva
vimhdglermygekqenvyyyittlnenyhmpa

SCOPe Domain Coordinates for d1rp7a1:

Click to download the PDB-style file with coordinates for d1rp7a1.
(The format of our PDB-style files is described here.)

Timeline for d1rp7a1: