SCOP 1.67: Domain d1rhm.2: 1rhm C:,D:

Lineage for d1rhm.2 (1rhm C:,D:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (2 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (7 proteins)

6. Protein Apopain (caspase-3, cpp32) [52131] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52132] (15 PDB entries)

8. Domain d1rhm.2: 1rhm C:,D: [97485]
   complexed with na4

Details for d1rhm.2

PDB Entry: 1rhm, 2.5 Å

PDB Description: crystal structure of the complex of caspase-3 with a nicotinic acid aldehyde inhibitor

SCOP Domain Sequences for d1rhm.2:

Sequence; same for both SEQRES and ATOM records:

>g1rhm.2 c.17.1.1 (C:,D:) Apopain (caspase-3, cpp32) {Human (Homo sapiens)}
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgieXkipveadflyaystapgyyswrnskdgswfiqslcamlk
qyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfy

Timeline for d1rhm.2:

• d1rhm.2 is new in SCOP 1.67
  
• d1rhm.2 appears in SCOP 1.69
  
• d1rhm.2 appears in the current release, SCOPe 2.08