SCOPe 2.08: Domain d1rg1a1: 1rg1 A:162-350

Lineage for d1rg1a1 (1rg1 A:162-350)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.136: Phospholipase D/nuclease [56023] (1 superfamily)
   beta-alpha-beta-alpha-beta-alpha-beta(4)-alpha; mixed sheet: order 1765234

4. Superfamily d.136.1: Phospholipase D/nuclease [56024] (6 families)

5. Family d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 [69815] (2 proteins)

6. Protein Tyrosyl-DNA phosphodiesterase TDP1 [69816] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69817] (36 PDB entries)

8. Domain d1rg1a1: 1rg1 A:162-350 [97415]
   protein/DNA complex; complexed with ots, spm, vo4

Details for d1rg1a1

PDB Entry: 1rg1, 2.1 Å

PDB Description: crystal structure of human tyrosyl-dna phosphodiesterase complexed with vanadate, octopamine, and tetranucleotide agtt

PDB Compounds: (A:) tyrosyl-DNA phosphodiesterase 1

SCOPe Domain Sequences for d1rg1a1:

Sequence; same for both SEQRES and ATOM records:

>d1rg1a1 d.136.1.3 (A:162-350) Tyrosyl-DNA phosphodiesterase TDP1 {Human (Homo sapiens) [TaxId: 9606]}
npfqfyltrvsgvkpkynsgalhikdilsplfgtlvssaqfnycfdvdwlvkqyppefrk
kpillvhgdkreakahlhaqakpyenislcqakldiafgthhtkmmlllyeeglrvviht
snlihadwhqktqgiwlsplypriadgthksgespthfkanlisyltaynapslkewidv
ihkhdlset

Timeline for d1rg1a1:

• d1rg1a1 first appeared in SCOP 1.67
  
• d1rg1a1 appears in SCOPe 2.07