SCOP 1.69: Domain d1rfib1: 1rfi B:162-350

Lineage for d1rfib1 (1rfi B:162-350)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.136: Phospholipase D/nuclease [56023] (1 superfamily)
   beta-alpha-beta-alpha-beta-alpha-beta(4)-alpha; mixed sheet: order 1765234

4. Superfamily d.136.1: Phospholipase D/nuclease [56024] (3 families)

5. Family d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 [69815] (1 protein)

6. Protein Tyrosyl-DNA phosphodiesterase TDP1 [69816] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69817] (12 PDB entries)

8. Domain d1rfib1: 1rfi B:162-350 [97382]

Details for d1rfib1

PDB Entry: 1rfi, 2.2 Å

PDB Description: crystal structure of human tyrosyl-dna phosphodiesterase complexed with vanadate, pentapeptide klnyk, and tetranucleotide agtc

SCOP Domain Sequences for d1rfib1:

Sequence; same for both SEQRES and ATOM records:

>d1rfib1 d.136.1.3 (B:162-350) Tyrosyl-DNA phosphodiesterase TDP1 {Human (Homo sapiens)}
npfqfyltrvsgvkpkynsgalhikdilsplfgtlvssaqfnycfdvdwlvkqyppefrk
kpillvhgdkreakahlhaqakpyenislcqakldiafgthhtkmmlllyeeglrvviht
snlihadwhqktqgiwlsplypriadgthksgespthfkanlisyltaynapslkewidv
ihkhdlset

Timeline for d1rfib1:

• d1rfib1 first appeared in SCOP 1.67
  
• d1rfib1 appears in SCOP 1.71
  
• d1rfib1 appears in the current release, SCOPe 2.08