SCOPe 2.07: Domain d1r8ka_: 1r8k A:

Lineage for d1r8ka_ (1r8k A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.3: PdxA-like [102656] (2 proteins)
   Pfam PF04166; contains extra beta-alpha unit between strands 2 and 3; closer relationships to the PlsX-like and phosphotransacetylase families

6. Protein 4-hydroxythreonine-4-phosphate dehydrogenase PdxA [102657] (2 species)
   pyridoxal phosphate biosynthetic protein

7. Species Salmonella typhimurium [TaxId:90371] [102659] (1 PDB entry)

8. Domain d1r8ka_: 1r8k A: [97240]
   complexed with cl, co, so4

Details for d1r8ka_

PDB Entry: 1r8k, 2.1 Å

PDB Description: pdxa protein; nad-dependent dehydrogenase/carboxylase; subunit of pyridoxine phosphate biosynthetic protein pdxj-pdxa [salmonella typhimurium]

PDB Compounds: (A:) 4-hydroxythreonine-4-phosphate dehydrogenase 1

SCOPe Domain Sequences for d1r8ka_:

Sequence; same for both SEQRES and ATOM records:

>d1r8ka_ c.77.1.3 (A:) 4-hydroxythreonine-4-phosphate dehydrogenase PdxA {Salmonella typhimurium [TaxId: 90371]}
saqrvvitpgepagsgpdlvvqlaqrawpielvvcadgallteraamlglplsllpyspd
vpaapqpagtltllpvslrapaisgqltvengpyvvetlaracdgclngefaalitgpvh
kgvindagisftghteffeersqakkvvmmlateelrvalatthlplraiadaitpallh
eviailhhdlrtkfgiaeprilvcglnphagegghmgteeidtiipvldelraqgmklng
plpadtlfqpkyldnadavlamyhdqglpvlkyqgfgrgvnitlglpfirtsvdhgtale
lagrgkadvgsfitalnlaikmivntq

Timeline for d1r8ka_:

• d1r8ka_ first appeared in SCOP 1.67
  
• d1r8ka_ appears in SCOPe 2.06
  
• d1r8ka_ appears in the current release, SCOPe 2.08