Lineage for d1r78a_ (1r78 A:)

  1. Root: SCOP 1.69
  2. 496776Class d: Alpha and beta proteins (a+b) [53931] (279 folds)
  3. 511959Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 511960Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 512001Family d.144.1.7: Protein kinases, catalytic subunit [88854] (53 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 512137Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 512147Species Human (Homo sapiens) [TaxId:9606] [88856] (79 PDB entries)
  8. 512178Domain d1r78a_: 1r78 A: [97190]

Details for d1r78a_

PDB Entry: 1r78 (more details), 2 Å

PDB Description: CDK2 complex with a 4-alkynyl oxindole inhibitor
PDB Compounds: (A:)

SCOP Domain Sequences for d1r78a_:

Sequence, based on SEQRES records: (download)

>d1r78a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d1r78a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkirltaireisllkelnhpnivklldv
ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
pqnllintegaikladfgvtlwyrapeillgckyystavdiwslgcifaemvtrralfpg
dseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsq
mlhydpnkrisakaalahpffqdvtkpvphlrl

SCOP Domain Coordinates for d1r78a_:

Click to download the PDB-style file with coordinates for d1r78a_.
(The format of our PDB-style files is described here.)

Timeline for d1r78a_: