SCOPe 2.05: Domain d1r66a_: 1r66 A:

Lineage for d1r66a_ (1r66 A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein dTDP-glucose 4,6-dehydratase (RmlB) [51755] (4 species)

7. Species Streptomyces venezuelae [TaxId:54571] [102133] (2 PDB entries)

8. Domain d1r66a_: 1r66 A: [97146]
   complexed with cl, nad, tyd

Details for d1r66a_

PDB Entry: 1r66, 1.44 Å

PDB Description: crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with nad and tyd bound

PDB Compounds: (A:) TDP-glucose-4,6-dehydratase

SCOPe Domain Sequences for d1r66a_:

Sequence; same for both SEQRES and ATOM records:

>d1r66a_ c.2.1.2 (A:) dTDP-glucose 4,6-dehydratase (RmlB) {Streptomyces venezuelae [TaxId: 54571]}
mrllvtggagfigshfvrqllagaypdvpadevivldsltyagnranlapvdadprlrfv
hgdirdagllarelrgvdaivhfaaeshvdrsiagasvftetnvqgtqtllqcavdagvg
rvvhvstdevygsidsgswtessplepnspyaaskagsdlvarayhrtygldvritrccn
nygpyqhpekliplfvtnlldggtlplygdganvrewvhtddhcrgialvlaggrageiy
higggleltnreltgilldslgadwssvrkvadrkghdlrysldggkierelgyrpqvsf
adglartvrwyrenrgwweplk

Timeline for d1r66a_:

• d1r66a_ first appeared in SCOP 1.67
  
• d1r66a_ appears in SCOPe 2.04
  
• d1r66a_ appears in SCOPe 2.06
  
• d1r66a_ appears in the current release, SCOPe 2.08