SCOPe 2.02: Domain d1r5wd2: 1r5w D:31-120

Lineage for d1r5wd2 (1r5w D:31-120)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (1 family)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)

6. Protein Class II MHC beta chain, N-terminal domain [88819] (15 species)

7. Species Mouse (Mus musculus), I-EK [TaxId:10090] [88827] (9 PDB entries)

8. Domain d1r5wd2: 1r5w D:31-120 [97131]
   Other proteins in same PDB: d1r5wa1, d1r5wa2, d1r5wb1, d1r5wc1, d1r5wc2, d1r5wd1

Details for d1r5wd2

PDB Entry: 1r5w, 2.9 Å

PDB Description: evidence that structural rearrangements and/or flexibility during tcr binding can contribute to t-cell activation

PDB Compounds: (D:) MHC H2-IE-beta

SCOPe Domain Sequences for d1r5wd2:

Sequence; same for both SEQRES and ATOM records:

>d1r5wd2 d.19.1.1 (D:31-120) Class II MHC beta chain, N-terminal domain {Mouse (Mus musculus), I-EK [TaxId: 10090]}
apwfleysksechfyngtqrvrllvryfynleenlrfdsdvgefravtelgrpdaenwns
qpefleqkraevdtvcrhnyeifdnflvpr

Timeline for d1r5wd2:

• d1r5wd2 first appeared in SCOP 1.67
  
• d1r5wd2 appears in SCOPe 2.01
  
• d1r5wd2 appears in SCOPe 2.03
  
• d1r5wd2 appears in the current release, SCOPe 2.08