SCOPe 2.07: Domain d1r4fa1: 1r4f A:2-327

Lineage for d1r4fa1 (1r4f A:2-327)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.70: Nucleoside hydrolase [53589] (1 superfamily)
   core: 3 layers, a/b/a ; mixed beta-sheet of 8 strands, order 32145687; strand 7 is antiparallel to the rest

4. Superfamily c.70.1: Nucleoside hydrolase [53590] (2 families)

5. Family c.70.1.1: Nucleoside hydrolase [53591] (5 proteins)
   automatically mapped to Pfam PF01156

6. Protein Inosine-adenosine-guanosine preferring nucleoside hydrolase [69587] (1 species)

7. Species Trypanosoma vivax [TaxId:5699] [69588] (5 PDB entries)

8. Domain d1r4fa1: 1r4f A:2-327 [96994]
   Other proteins in same PDB: d1r4fa2, d1r4fb2
   complexed with ad3, ca; mutant

Details for d1r4fa1

PDB Entry: 1r4f, 2.3 Å

PDB Description: inosine-adenosine-guanosine preferring nucleoside hydrolase from trypanosoma vivax: trp260ala mutant in complex with 3-deaza-adenosine

PDB Compounds: (A:) IAG-nucleoside hydrolase

SCOPe Domain Sequences for d1r4fa1:

Sequence, based on SEQRES records:

>d1r4fa1 c.70.1.1 (A:2-327) Inosine-adenosine-guanosine preferring nucleoside hydrolase {Trypanosoma vivax [TaxId: 5699]}
aknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnnm
nlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqqll
adlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstdg
taewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgtm
wamcthcellrdgdgyyaadaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaen
ypltfvarnpeaeffldmllrsarac

Sequence, based on observed residues (ATOM records):

>d1r4fa1 c.70.1.1 (A:2-327) Inosine-adenosine-guanosine preferring nucleoside hydrolase {Trypanosoma vivax [TaxId: 5699]}
aknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnnm
nlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqqll
adlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstdg
taewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgtm
wamyaadaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaenypltfvarnpeae
ffldmllrsarac

Timeline for d1r4fa1:

• d1r4fa1 first appeared in SCOP 1.67, called d1r4fa_
  
• d1r4fa1 appears in SCOPe 2.06
  
• d1r4fa1 appears in the current release, SCOPe 2.08