Lineage for d1r42a_ (1r42 A:)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 729090Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 729091Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (15 families) (S)
  5. 729182Family d.92.1.5: Neurolysin-like [55505] (4 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 729183Protein Angiotensin converting enzyme 2, ACE2 [103125] (1 species)
  7. 729184Species Human (Homo sapiens) [TaxId:9606] [103126] (3 PDB entries)
  8. 729187Domain d1r42a_: 1r42 A: [96968]
    complexed with collectrin homology domain (disordered segments), chains B, C, D and E
    complexed with cl, nag, zn

Details for d1r42a_

PDB Entry: 1r42 (more details), 2.2 Å

PDB Description: native human angiotensin converting enzyme-related carboxypeptidase (ace2)
PDB Compounds: (A:) angiotensin I converting enzyme 2

SCOP Domain Sequences for d1r42a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1r42a_ d.92.1.5 (A:) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens) [TaxId: 9606]}
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

SCOP Domain Coordinates for d1r42a_:

Click to download the PDB-style file with coordinates for d1r42a_.
(The format of our PDB-style files is described here.)

Timeline for d1r42a_: