SCOP 1.69: Domain d1r42a_: 1r42 A:

Lineage for d1r42a_ (1r42 A:)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (15 families)

5. Family d.92.1.5: Neurolysin-like [55505] (4 proteins)
   combines M2, M3 and M32 families of metalloproteases
   the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

6. Protein Angiotensin converting enzyme 2, ACE2 [103125] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [103126] (2 PDB entries)

8. Domain d1r42a_: 1r42 A: [96968]
   complexed with collectrin homology domain (disordered segments), chains B, C, D and E

Details for d1r42a_

PDB Entry: 1r42, 2.2 Å

PDB Description: native human angiotensin converting enzyme-related carboxypeptidase (ace2)

SCOP Domain Sequences for d1r42a_:

Sequence; same for both SEQRES and ATOM records:

>d1r42a_ d.92.1.5 (A:) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens)}
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

Timeline for d1r42a_:

• d1r42a_ first appeared in SCOP 1.67
  
• d1r42a_ appears in SCOP 1.71
  
• d1r42a_ appears in the current release, SCOPe 2.08