SCOPe 2.08: Domain d1q8ja1: 1q8j A:301-559

Lineage for d1q8ja1 (1q8j A:301-559)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.21: Dihydropteroate synthetase-like [51717] (3 families)

5. Family c.1.21.2: Methyltetrahydrofolate-utiluzing methyltransferases [51723] (3 proteins)

6. Protein Cobalamin-dependent methionine synthase MetH, C-terminal domain [102104] (1 species)
   5-methyltetrahydrofolate homocysteine S-methyltransferase

7. Species Thermotoga maritima [TaxId:2336] [102105] (8 PDB entries)

8. Domain d1q8ja1: 1q8j A:301-559 [96210]
   Other proteins in same PDB: d1q8ja2, d1q8jb2
   complexed with c2f, cd, hcs

Details for d1q8ja1

PDB Entry: 1q8j, 1.9 Å

PDB Description: cobalamin-dependent methionine synthase (1-566) from thermotoga maritima (cd2+, hcy, methyltetrahydrofolate complex)

PDB Compounds: (A:) 5-methyltetrahydrofolate S-homocysteine methyltransferase

SCOPe Domain Sequences for d1q8ja1:

Sequence; same for both SEQRES and ATOM records:

>d1q8ja1 c.1.21.2 (A:301-559) Cobalamin-dependent methionine synthase MetH, C-terminal domain {Thermotoga maritima [TaxId: 2336]}
favsspsklvtfdhfvvigerinpagrkklwaemqkgneeivikeaktqvekgaevldvn
fgiesqidvryvekivqtlpyvsnvplsldiqnvdlteralraypgrslfnsakvdeeel
emkinllkkyggtlivllmgkdvpksfeerkeyfekalkilerhdfsdrvifdpgvlplg
aegkpvevlktiefisskgfnttvglsnlsfglpdrsyyntaflvlgiskglssaimnpl
detlmktlnatlvilekke

Timeline for d1q8ja1:

• d1q8ja1 first appeared in SCOP 1.67
  
• d1q8ja1 appears in SCOPe 2.07