SCOP 1.71: Domain d1q8ia1: 1q8i A:2-389

Lineage for d1q8ia1 (1q8i A:2-389)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (10 families)
   consists of one domain of this fold

5. Family c.55.3.5: DnaQ-like 3'-5' exonuclease [53118] (10 proteins)
   contains Pfam 00929

6. Protein Exonuclease domain of family B DNA polymerases [53125] (8 species)
   elaborated with additional structures and the N-terminal subdomain

7. Species Escherichia coli [TaxId:562] [102482] (1 PDB entry)
   DNA polymerase II, additional N-terminal subdomain has an OB-fold with a ferredoxin-like fold insertion

8. Domain d1q8ia1: 1q8i A:2-389 [96208]
   Other proteins in same PDB: d1q8ia2
   mutant

Details for d1q8ia1

PDB Entry: 1q8i, 2 Å

PDB Description: crystal structure of escherichia coli dna polymerase ii

SCOP Domain Sequences for d1q8ia1:

Sequence, based on SEQRES records:

>d1q8ia1 c.55.3.5 (A:2-389) Exonuclease domain of family B DNA polymerases {Escherichia coli}
aqagfiltrhwrdtpqgtevsfwlatdngplqvtlapqesvafipadqvpraqhilqgeq
gfrltplalkdfhrqpvyglycrahrqlmnyekrlreggvtvyeadvrpperylmerfit
spvwvegdmhngtivnarlkphpdyrpplkwvsidiettrhgelyciglegcgqrivyml
gpengdassldfeleyvasrpqlleklnawfanydpdviigwnvvqfdlrmlqkhaeryr
lplrlgrdnselewrehgfkngvffaqakgrliidgiealksafwnfssfsletvaqell
gegksidnpwdrmdeidrrfaedkpalatynlkdcelvtqifhkteimpflleratvngl
pvdrhggsvaafghlyfprmhragyvap

Sequence, based on observed residues (ATOM records):

>d1q8ia1 c.55.3.5 (A:2-389) Exonuclease domain of family B DNA polymerases {Escherichia coli}
aqagfiltrhwrdtpqgtevsfwlatdngplqvtlapqesvafipadqvpraqhilqgeq
gfrltplalkdfhrqpvyglycrahrqlmnyekrlreggvtvyeadvrpperylmerfit
spvwvegdmhngtivnarlkphpdyrpplkwvsidiettrhgelyciglegcgqrivyml
gpengdassldfeleyvasrpqlleklnawfanydpdviigwnvvqfdlrmlqkhaeryr
lplrlgrdnselewrehgfkngvffaqakgrliidgiealksafwnfssfsletvaqell
mdeidrrfaedkpalatynlkdcelvtqifhkteimpflleratvnglpvdrhggsvaaf
ghlyfprmhragyvap

Timeline for d1q8ia1:

• d1q8ia1 first appeared in SCOP 1.67
  
• d1q8ia1 appears in SCOP 1.69
  
• d1q8ia1 appears in SCOP 1.73
  
• d1q8ia1 appears in the current release, SCOPe 2.08