SCOPe 2.08: Domain d1q6ma1: 1q6m A:1-285

Lineage for d1q6ma1 (1q6m A:1-285)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
   has an extension to the beta-sheet of 3 antiparallel strands before strand 4

6. Protein Tyrosine phosphatase [52806] (7 species)

7. Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (268 PDB entries)
   Uniprot P18031 2-300 ! Uniprot P18031 1-298 ! Uniprot P18031 2-299

8. Domain d1q6ma1: 1q6m A:1-285 [95983]
   Other proteins in same PDB: d1q6ma2
   complexed with p27

Details for d1q6ma1

PDB Entry: 1q6m, 2.2 Å

PDB Description: the structure of phosphotyrosine phosphatase 1b in complex with compound 3

PDB Compounds: (A:) protein-tyrosine phosphatase, non-receptor type 1

SCOPe Domain Sequences for d1q6ma1:

Sequence; same for both SEQRES and ATOM records:

>d1q6ma1 c.45.1.2 (A:1-285) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}
memekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklh
qedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslk
caqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwp
dfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkd
pssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgds

Timeline for d1q6ma1:

• d1q6ma1 first appeared in SCOP 1.67, called d1q6ma_
  
• d1q6ma1 appears in SCOPe 2.07