Lineage for d1q43b_ (1q43 B:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2070014Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2071306Superfamily b.82.3: cAMP-binding domain-like [51206] (4 families) (S)
  5. 2071312Family b.82.3.2: cAMP-binding domain [51210] (13 protein domains)
    Pfam PF00027
  6. 2071401Protein HCN pacemaker channel [101993] (1 species)
    potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel
  7. 2071402Species Mouse (Mus musculus) [TaxId:10090] [101994] (5 PDB entries)
  8. 2071410Domain d1q43b_: 1q43 B: [95778]
    complexed with cmp

Details for d1q43b_

PDB Entry: 1q43 (more details), 2 Å

PDB Description: HCN2I 443-640 in the presence of cAMP, selenomethionine derivative
PDB Compounds: (B:) Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

SCOPe Domain Sequences for d1q43b_:

Sequence, based on SEQRES records: (download)

>d1q43b_ b.82.3.2 (B:) HCN pacemaker channel {Mouse (Mus musculus) [TaxId: 10090]}
srrqyqekykqveqymsfhklpadfrqkihdyyehryqgkmfdedsilgelngplreeiv
nfncrklvasmplfanadpnfvtamltklkfevfqpgdyiiregtigkkmyfiqhgvvsv
ltkgnkemklsdgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevleeypmmrra
fetvaidrldri

Sequence, based on observed residues (ATOM records): (download)

>d1q43b_ b.82.3.2 (B:) HCN pacemaker channel {Mouse (Mus musculus) [TaxId: 10090]}
srrqyqekykqveqymsfhklpadfrqkihdyyehryqgkmfdedsilgelngplreeiv
nfncrklvasmplfanadpnfvtamltklkfevfqpgdyiiregtigkkmyfiqhgvvsv
ltemklsdgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevleeypmmrrafetv
aidrldri

SCOPe Domain Coordinates for d1q43b_:

Click to download the PDB-style file with coordinates for d1q43b_.
(The format of our PDB-style files is described here.)

Timeline for d1q43b_: