SCOPe 2.08: Domain d1q17c1: 1q17 C:1-294

Lineage for d1q17c1 (1q17 C:1-294)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
   silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain

6. Protein Hst2 [102294] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [102295] (5 PDB entries)
   Uniprot P53686 1-293

8. Domain d1q17c1: 1q17 C:1-294 [95552]
   Other proteins in same PDB: d1q17a2, d1q17b2, d1q17c2
   complexed with apr, cl, zn

Details for d1q17c1

PDB Entry: 1q17, 2.7 Å

PDB Description: Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide

PDB Compounds: (C:) HST2 protein

SCOPe Domain Sequences for d1q17c1:

Sequence, based on SEQRES records:

>d1q17c1 c.31.1.5 (C:1-294) Hst2 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
msvstastemsvrkiaahmksnpnakvifmvgagistscgipdfrspgtglyhnlarlkl
pypeavfdvdffqsdplpfytlakelypgnfrpskfhyllklfqdkdvlkrvytqnidtl
erqagvkddliieahgsfahchcigcgkvyppqvfksklaehpikdfvkcdvcgelvkpa
ivffgedlpdsfsetwlndsewlrekittsgkhpqqplvivvgtslavypfaslpeeipr
kvkrvlcnletvgdfkankrptdlivhqysdefaeqlveelgwqedfekiltaq

Sequence, based on observed residues (ATOM records):

>d1q17c1 c.31.1.5 (C:1-294) Hst2 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
msvstastemsvrkiaahmksnpnakvifmvgagistscgipdfrspgtglyhnlarlkl
pypeavfdvdffqsdplpfytlakelypgnfrpskfhyllklfqdkdvlkrvytqnidtl
erqagvkddliieahgsfahchcigcgkvyppqvfksklaehpikdfvkcdvcgelvkpa
ivffgedlpdsfsetwlndsewlrekikhpqqplvivvgtslavypfaslpeeiprkvkr
vlcnletvgdfkankrptdlivhqysdefaeqlveelgwqedfekiltaq

Timeline for d1q17c1:

• d1q17c1 first appeared in SCOP 1.67, called d1q17c_
  
• d1q17c1 appears in SCOPe 2.07