SCOPe 2.05: Domain d1pyo.1: 1pyo A:,B:

Lineage for d1pyo.1 (1pyo A:,B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Caspase-2 [102528] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102529] (1 PDB entry)

8. Domain d1pyo.1: 1pyo A:,B: [95370]

Details for d1pyo.1

PDB Entry: 1pyo, 1.65 Å

PDB Description: Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho

PDB Compounds: (A:) Caspase-2, (B:) Caspase-2

SCOPe Domain Sequences for d1pyo.1:

Sequence; same for both SEQRES and ATOM records:

>g1pyo.1 c.17.1.1 (A:,B:) Caspase-2 {Human (Homo sapiens) [TaxId: 9606]}
lqvkpctpefyqthfqlayrlqsrprglalvlsnvhftgekelefrsggdvdhstlvtlf
kllgydvhvlcdqtaqemqeklqnfaqlpahrvtdscivallshgvegaiygvdgkllql
qevfqlfdnancpslqnkpkmffiqacrgdetdrgvdqqXpkmrlptrsdmicgyaclkg
taamrntkrgswyiealaqvfseracdmhvadmlvkvnalikdregyapgtefhrckems
eycstlcrhlylfpghpp

Timeline for d1pyo.1:

• d1pyo.1 first appeared in SCOP 1.67
  
• d1pyo.1 appears in SCOPe 2.04
  
• d1pyo.1 appears in SCOPe 2.06
  
• d1pyo.1 appears in the current release, SCOPe 2.08