SCOP 1.67: Domain d1pxxb1: 1pxx B:1074-1583

Lineage for d1pxxb1 (1pxx B:1074-1583)

1. Root: SCOP 1.67

2. Class a: All alpha proteins [46456] (202 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (3 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (2 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Mouse (Mus musculus) [TaxId:10090] [48138] (8 PDB entries)

8. Domain d1pxxb1: 1pxx B:1074-1583 [95309]
   Other proteins in same PDB: d1pxxa2, d1pxxb2, d1pxxc2, d1pxxd2

Details for d1pxxb1

PDB Entry: 1pxx, 2.9 Å

PDB Description: crystal structure of diclofenac bound to the cyclooxygenase active site of cox-2

SCOP Domain Sequences for d1pxxb1:

Sequence; same for both SEQRES and ATOM records:

>d1pxxb1 a.93.1.2 (B:1074-1583) Prostaglandin H2 synthase {Mouse (Mus musculus)}
fltriklllkptpntvhyilthfkgvwnivnnipflrslimkyvltsrsylidspptynv
hygyksweafsnlsyytralppvaddcptpmgvkgnkelpdskevlekvllrrefipdpq
gsnmmfaffaqhfthqffktdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgkl
kyqviggevypptvkdtqvemiypphipenlqfavgqevfglvpglmmyatiwlrehnrv
cdilkqehpewgdeqlfqtsrliligetikiviedyvqhlsgyhfklkfdpellfnqqfq
yqnriasefntlyhwhpllpdtfniedqeysfkqflynnsillehgltqfvesftrqiag
rvaggrnvpiavqavakasidqsremkyqslneyrkrfslkpytsfeeltgekemaaelk
alysdidvmelypallvekprpdaifgetmvelgapfslkglmgnpicspqywkpstfgg
evgfkiintasiqslicnnvkgcpftsfnvq

Timeline for d1pxxb1:

• d1pxxb1 is new in SCOP 1.67
  
• d1pxxb1 appears in SCOP 1.69
  
• d1pxxb1 appears in the current release, SCOPe 2.08