Lineage for d1pwwb3 (1pww B:264-550)

  1. Root: SCOP 1.67
  2. 405194Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
  3. 421044Fold d.166: ADP-ribosylation [56398] (1 superfamily)
    unusual fold
  4. 421045Superfamily d.166.1: ADP-ribosylation [56399] (3 families) (S)
  5. 421046Family d.166.1.1: ADP-ribosylating toxins [56400] (9 proteins)
  6. 421047Protein Anthrax toxin lethal factor, middle domain [69845] (1 species)
    includes an all-alpha insert subdomain
  7. 421048Species Bacillus anthracis [TaxId:1392] [69846] (7 PDB entries)
  8. 421058Domain d1pwwb3: 1pww B:264-550 [95261]
    Other proteins in same PDB: d1pwwa1, d1pwwa2, d1pwwb1, d1pwwb2
    complexed with an optimized peptide substrate (chains C and D) in the presence of zinc
    complexed with zn; mutant

Details for d1pwwb3

PDB Entry: 1pww (more details), 2.8 Å

PDB Description: crystal structure of anthrax lethal factor active site mutant protein complexed with an optimised peptide substrate in the presence of zinc.

SCOP Domain Sequences for d1pwwb3:

Sequence, based on SEQRES records: (download)

>d1pwwb3 d.166.1.1 (B:264-550) Anthrax toxin lethal factor, middle domain {Bacillus anthracis}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkldi
qpydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmni
nnltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwri
qlspdtragylengklilqrnigleikdvqiikqsekeyiridakvv

Sequence, based on observed residues (ATOM records): (download)

>d1pwwb3 d.166.1.1 (B:264-550) Anthrax toxin lethal factor, middle domain {Bacillus anthracis}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslsnplsekekeflkklkldiqpydinqrlqdtggl
idspsinldvrkqykrdiqnidallhqsigstlynkiylyenmninnltatlgadlvdst
dntkinrgifnefkknfkysissnymivdinerpaldnerlkwriqlspdtragylengk
lilqrnigleikdvqiikqsekeyiridakvv

SCOP Domain Coordinates for d1pwwb3:

Click to download the PDB-style file with coordinates for d1pwwb3.
(The format of our PDB-style files is described here.)

Timeline for d1pwwb3: