Lineage for d1pwwa3 (1pww A:264-550)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 3000428Fold d.166: ADP-ribosylation [56398] (1 superfamily)
    unusual fold
  4. 3000429Superfamily d.166.1: ADP-ribosylation [56399] (8 families) (S)
  5. 3000430Family d.166.1.1: ADP-ribosylating toxins [56400] (10 proteins)
  6. 3000431Protein Anthrax toxin lethal factor, middle domain [69845] (1 species)
    includes an all-alpha insert subdomain
  7. 3000432Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [69846] (9 PDB entries)
  8. 3000444Domain d1pwwa3: 1pww A:264-550 [95258]
    Other proteins in same PDB: d1pwwa1, d1pwwa2, d1pwwb1, d1pwwb2
    complexed with an optimized peptide substrate (chains C and D) in the presence of zinc
    complexed with zn; mutant

Details for d1pwwa3

PDB Entry: 1pww (more details), 2.8 Å

PDB Description: crystal structure of anthrax lethal factor active site mutant protein complexed with an optimised peptide substrate in the presence of zinc.
PDB Compounds: (A:) Lethal Factor

SCOPe Domain Sequences for d1pwwa3:

Sequence, based on SEQRES records: (download)

>d1pwwa3 d.166.1.1 (A:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkldi
qpydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmni
nnltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwri
qlspdtragylengklilqrnigleikdvqiikqsekeyiridakvv

Sequence, based on observed residues (ATOM records): (download)

>d1pwwa3 d.166.1.1 (A:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidilsekekeflkklkldiqpydinqrlqdtgglidspsin
ldvrkqykrdiqnidallhqsigstlynkiylyenmninnltatlgadlvdstdntkinr
gifnefkknfkysissnymivdinerpaldnerlkwriqlspdtragylengklilqrni
gleikdvqiikqsekeyiridakvv

SCOPe Domain Coordinates for d1pwwa3:

Click to download the PDB-style file with coordinates for d1pwwa3.
(The format of our PDB-style files is described here.)

Timeline for d1pwwa3: