SCOPe 2.07: Domain d1pwpb3: 1pwp B:264-550

Lineage for d1pwpb3 (1pwp B:264-550)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.166: ADP-ribosylation [56398] (1 superfamily)
   unusual fold

4. Superfamily d.166.1: ADP-ribosylation [56399] (8 families)

5. Family d.166.1.1: ADP-ribosylating toxins [56400] (10 proteins)

6. Protein Anthrax toxin lethal factor, middle domain [69845] (1 species)
   includes an all-alpha insert subdomain

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [69846] (9 PDB entries)

8. Domain d1pwpb3: 1pwp B:264-550 [95237]
   Other proteins in same PDB: d1pwpa1, d1pwpa2, d1pwpb1, d1pwpb2
   complexed with small molecule inhibitor
   complexed with nsc, zn

Details for d1pwpb3

PDB Entry: 1pwp, 2.9 Å

PDB Description: Crystal Structure of the Anthrax Lethal Factor complexed with Small Molecule Inhibitor NSC 12155

PDB Compounds: (B:) Lethal Factor

SCOPe Domain Sequences for d1pwpb3:

Sequence, based on SEQRES records:

>d1pwpb3 d.166.1.1 (B:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkldi
qpydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmni
nnltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwri
qlspdtragylengklilqrnigleikdvqiikqsekeyiridakvv

Sequence, based on observed residues (ATOM records):

>d1pwpb3 d.166.1.1 (B:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslseeekellnrdssnplsekekeflkklkldiqpy
dinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmninnl
tatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwriqls
pdtragylengklilqrnigleikdvqiikqsekeyiridakvv

Timeline for d1pwpb3:

• d1pwpb3 first appeared in SCOP 1.67
  
• d1pwpb3 appears in SCOPe 2.06
  
• d1pwpb3 appears in the current release, SCOPe 2.08