SCOP 1.67: Domain d1pwma_: 1pwm A:

Lineage for d1pwma_ (1pwm A:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (28 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (1 family)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (14 proteins)
   Common fold covers whole protein structure

6. Protein Aldose reductase (aldehyde reductase) [51436] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [51437] (16 PDB entries)

8. Domain d1pwma_: 1pwm A: [95231]
   complexed with cl, fid, nap

Details for d1pwma_

PDB Entry: 1pwm, 0.92 Å

PDB Description: crystal structure of human aldose reductase complexed with nadp and fidarestat

SCOP Domain Sequences for d1pwma_:

Sequence; same for both SEQRES and ATOM records:

>d1pwma_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Human (Homo sapiens)}
masrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfheef

Timeline for d1pwma_:

• d1pwma_ is new in SCOP 1.67
  
• d1pwma_ appears in SCOP 1.69
  
• d1pwma_ appears in the current release, SCOPe 2.08