Lineage for d1pwla_ (1pwl A:)

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 383642Fold c.1: TIM beta/alpha-barrel [51350] (28 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 384272Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (1 family) (S)
  5. 384273Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (14 proteins)
    Common fold covers whole protein structure
  6. 384299Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 384300Species Human (Homo sapiens) [TaxId:9606] [51437] (16 PDB entries)
  8. 384303Domain d1pwla_: 1pwl A: [95230]
    complexed with bfi, nap

Details for d1pwla_

PDB Entry: 1pwl (more details), 1.1 Å

PDB Description: crystal structure of human aldose reductase complexed with nadp and minalrestat

SCOP Domain Sequences for d1pwla_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1pwla_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Human (Homo sapiens)}
masrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfheef

SCOP Domain Coordinates for d1pwla_:

Click to download the PDB-style file with coordinates for d1pwla_.
(The format of our PDB-style files is described here.)

Timeline for d1pwla_: